Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 1.461


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMARCA1chrX_-_128485121-0.543.1e-02Click!
SMARCC2chr12_-_548695680.421.0e-01Click!
NCOR1chr17_-_15914485-0.224.1e-01Click!
DMAP1chr1_+_444516980.087.7e-01Click!
NCOR2chr12_-_123617962-0.039.2e-01Click!
SMARCA5chr4_+_144654005-0.029.4e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_149004916 2.404 NM_004079
CTSS
cathepsin S
chrX_+_78087484 2.159 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr15_+_42815851 1.841 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chr1_+_32512298 1.792 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr7_+_106293112 1.699 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_73826244 1.529 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr4_-_153820535 1.497 NM_152680
TMEM154
transmembrane protein 154
chrX_-_30505804 1.439 NM_025159
CXorf21
chromosome X open reading frame 21
chr13_-_102517196 1.419 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr1_+_100957883 1.353 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr5_+_140235114 1.258 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr2_-_37752731 1.234 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr3_+_120799411 1.217 NM_015900
PLA1A
phospholipase A1 member A
chr22_+_38652555 1.202 GRAP2
GRB2-related adaptor protein 2
chrX_+_37524190 1.151 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr1_-_149004879 1.142 CTSS
cathepsin S
chr5_-_169657312 1.100 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr12_+_11694172 1.083 ETV6
ets variant 6
chr12_-_15005761 1.070 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr20_+_44180355 1.055 CD40
CD40 molecule, TNF receptor superfamily member 5
chr5_-_169657395 1.054 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_-_26665213 1.053 EVI2B
ecotropic viral integration site 2B
chr5_+_169592523 1.032 NM_001102609
C5orf58
chromosome 5 open reading frame 58
chr3_+_123279439 1.022 NM_006889
CD86
CD86 molecule
chr4_-_40211324 0.997 RBM47
RNA binding motif protein 47
chr4_-_47831002 0.988 NM_003328
TXK
TXK tyrosine kinase
chr1_-_205161821 0.977 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr20_+_44180296 0.972 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr3_-_123766113 0.969 NM_001146103
NM_031458
PARP9

poly (ADP-ribose) polymerase family, member 9

chr5_-_169657192 0.968 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr6_+_70633168 0.965 NM_001858
COL19A1
collagen, type XIX, alpha 1
chr17_-_31231421 0.937 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr8_-_114518194 0.935 NM_052900
NM_198123
CSMD3

CUB and Sushi multiple domains 3

chr6_-_33016561 0.926 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr3_+_188568861 0.925 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr1_+_196874839 0.916 PTPRC
protein tyrosine phosphatase, receptor type, C
chr14_+_75058591 0.905 BATF
basic leucine zipper transcription factor, ATF-like
chrX_+_37524250 0.897 CYBB
cytochrome b-245, beta polypeptide
chr1_+_32438788 0.896 NM_024296
CCDC28B
coiled-coil domain containing 28B
chr1_+_196874759 0.895 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr5_-_169657360 0.893 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr13_-_46368968 0.885 NM_000621
NM_001165947
HTR2A

5-hydroxytryptamine (serotonin) receptor 2A

chr15_+_86983038 0.879 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr13_-_45654327 0.874 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_54646061 0.863 NM_006928
PMEL
premelanosome protein
chr14_+_75058518 0.851 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr18_+_53170718 0.838 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr12_+_25096472 0.823 NM_006152
LRMP
lymphoid-restricted membrane protein
chr3_+_182900081 0.814 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr9_+_126460511 0.810


chr5_-_138753443 0.795 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr22_+_38627031 0.794 NM_004810
GRAP2
GRB2-related adaptor protein 2
chr15_-_87565813 0.782 NM_000326
RLBP1
retinaldehyde binding protein 1
chr1_-_149004852 0.773 CTSS
cathepsin S
chr8_-_40874485 0.765 NM_001135731
NM_024645
ZMAT4

zinc finger, matrin-type 4

chr21_-_33107813 0.763 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr17_+_44643067 0.761 ABI3
ABI family, member 3
chr10_-_49792282 0.757 NM_001006939
LRRC18
leucine rich repeat containing 18
chr1_+_32489426 0.743 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr2_-_213723298 0.735 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr2_+_143603439 0.733 ARHGAP15
Rho GTPase activating protein 15
chr11_+_5602782 0.720 NM_021616
TRIM34
tripartite motif containing 34
chr19_+_17723285 0.708 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr10_-_118887801 0.699 NM_001112704
NM_199131
VAX1

ventral anterior homeobox 1

chr17_+_6600080 0.688 XAF1
XIAP associated factor 1
chr1_-_159306327 0.688 ARHGAP30
Rho GTPase activating protein 30
chr3_-_113495763 0.685 NM_183061
SLC9A10
solute carrier family 9, member 10
chr14_+_93455010 0.679 NM_138344
FAM181A
family with sequence similarity 181, member A
chr8_-_102872354 0.679 NCALD
neurocalcin delta
chr16_+_48865521 0.676 ADCY7
adenylate cyclase 7
chr4_+_113437947 0.662 NM_001102406
NM_025144
ALPK1

alpha-kinase 1

chr4_-_169476391 0.653 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr1_-_47468029 0.647 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr16_+_55580910 0.634 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr1_+_938709 0.632 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr12_+_5023345 0.624 NM_002234
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr12_+_106692291 0.611 NM_203436
ASCL4
achaete-scute complex homolog 4 (Drosophila)
chr1_+_67404756 0.605 NM_144701
IL23R
interleukin 23 receptor
chr1_+_165564904 0.599 NM_001198783
POU2F1
POU class 2 homeobox 1
chr2_+_143603368 0.595 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr3_-_49826221 0.594 UBA7
ubiquitin-like modifier activating enzyme 7
chr10_-_14412813 0.594 NM_018027
FRMD4A
FERM domain containing 4A
chr1_-_159306369 0.590 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr16_+_11966464 0.586 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr15_-_42790805 0.581


chr1_-_165754325 0.580 NM_000734
NM_198053
CD247

CD247 molecule

chr3_+_14691609 0.579 NM_001184957
NM_001184958
NM_032137
C3orf20


chromosome 3 open reading frame 20


chr1_+_78888064 0.579 NM_006417
IFI44
interferon-induced protein 44
chr19_-_44518465 0.576 GMFG
glia maturation factor, gamma
chr17_+_6599879 0.571 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr6_+_154449334 0.562 NM_001145287
OPRM1
opioid receptor, mu 1
chr1_-_12880674 0.560 NM_001039361
PRAMEF10
PRAME family member 10
chr19_-_10074332 0.558 NM_031917
ANGPTL6
angiopoietin-like 6
chr3_-_123765767 0.556 NM_001146102
NM_001146105
NM_001146104
NM_001146106
PARP9



poly (ADP-ribose) polymerase family, member 9



chr17_-_26665144 0.556 EVI2B
ecotropic viral integration site 2B
chr1_+_159943385 0.552 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr6_+_52159143 0.540 NM_002190
IL17A
interleukin 17A
chr4_+_3220564 0.535 NM_001042690
C4orf44
chromosome 4 open reading frame 44
chr10_+_91051685 0.528 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr7_+_28418668 0.526 NM_182898
CREB5
cAMP responsive element binding protein 5
chr15_+_40353076 0.525 GANC
glucosidase, alpha; neutral C
chr1_-_115039614 0.521 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr6_-_36412562 0.519 NM_001010903
C6orf222
chromosome 6 open reading frame 222
chrX_-_111212659 0.518 NM_012471
TRPC5
transient receptor potential cation channel, subfamily C, member 5
chr11_+_128068982 0.517 NM_002017
FLI1
Friend leukemia virus integration 1
chr12_-_10173947 0.515 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr12_-_119961143 0.514 NM_003733
NM_198213
OASL

2'-5'-oligoadenylate synthetase-like

chr19_-_44518516 0.511 NM_004877
GMFG
glia maturation factor, gamma
chr6_-_31740466 0.508 GPANK1
G patch domain and ankyrin repeats 1
chr12_+_40117751 0.503 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr13_+_42034871 0.496 NM_033012
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr18_+_29573152 0.496 ASXL3
additional sex combs like 3 (Drosophila)
chr10_-_7491204 0.496 NM_001018039
SFMBT2
Scm-like with four mbt domains 2
chr6_+_31647854 0.495 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr11_-_104421240 0.495 NM_001017534
NM_052889
CARD16

CASP1
caspase recruitment domain family, member 16

caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr16_+_10878539 0.492 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr1_+_156416360 0.490 NM_001766
CD1D
CD1d molecule
chr2_+_102401580 0.489 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr14_+_99601498 0.487 NM_016337
EVL
Enah/Vasp-like
chr7_+_119700924 0.486 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr11_-_104411065 0.484 NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CASP1




caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr15_+_70477707 0.481 NM_001080462
TMEM202
transmembrane protein 202
chr11_-_64327197 0.479 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr21_+_42792810 0.478 NM_018964
SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr4_+_39874921 0.477 NM_004310
RHOH
ras homolog gene family, member H
chr4_-_38482805 0.477 NM_003263
TLR1
toll-like receptor 1
chr5_-_101862447 0.476 NM_173488
SLCO6A1
solute carrier organic anion transporter family, member 6A1
chrX_-_80344096 0.475 NM_030763
HMGN5
high-mobility group nucleosome binding domain 5
chrX_+_79562601 0.475 NM_152630
FAM46D
family with sequence similarity 46, member D
chr3_-_188903038 0.472 NM_001004312
RTP2
receptor (chemosensory) transporter protein 2
chr1_+_243384868 0.472 NM_018012
KIF26B
kinesin family member 26B
chr4_+_89519134 0.470 HERC6
hect domain and RLD 6
chr2_-_215711313 0.466 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chrX_+_135397790 0.465 NM_001727
BRS3
bombesin-like receptor 3
chr1_-_156816312 0.459 NM_001004477
OR10X1
olfactory receptor, family 10, subfamily X, member 1
chr1_+_120640507 0.455 NM_001100910
FAM72B
FAM72D
family with sequence similarity 72, member B
family with sequence similarity 72, member D
chr17_-_64649608 0.455 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr10_+_91142301 0.454 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr11_+_130745580 0.453 NM_001048209
NTM
neurotrimin
chr12_+_25096755 0.450 LRMP
lymphoid-restricted membrane protein
chr2_+_218641982 0.450 NM_198483
RUFY4
RUN and FYVE domain containing 4
chr6_-_108252200 0.449 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr17_-_26665194 0.448 EVI2B
ecotropic viral integration site 2B
chr20_-_43608429 0.445 NM_181502
SPINLW1
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
chr8_+_142501188 0.445 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chrX_-_54841397 0.444 NM_198510
ITIH5L
inter-alpha (globulin) inhibitor H5-like
chr12_-_119038940 0.444 RAB35
RAB35, member RAS oncogene family
chr17_+_8183912 0.443 NM_153007
ODF4
outer dense fiber of sperm tails 4
chr3_-_158704056 0.442 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr1_-_9052253 0.442 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr14_+_63750611 0.442 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr12_+_11693909 0.441 ETV6
ets variant 6
chr17_-_31441390 0.433 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr17_-_44642934 0.432 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chrX_-_110400406 0.431 NM_014289
CAPN6
calpain 6
chr3_-_64647325 0.431 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr12_+_49922592 0.428 DAZAP2
DAZ associated protein 2
chr17_-_26665220 0.428 NM_006495
EVI2B
ecotropic viral integration site 2B
chr11_+_303852 0.424 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr5_-_138803037 0.422 DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr7_+_150013716 0.422 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr12_-_119038995 0.422 NM_001167606
NM_006861
RAB35

RAB35, member RAS oncogene family

chrX_+_28515479 0.418 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr11_-_102100833 0.412 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr4_-_145281237 0.407 NM_002099
GYPA
glycophorin A (MNS blood group)
chr3_+_190831909 0.406 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr1_+_156716290 0.404 NM_001004472
OR10R2
olfactory receptor, family 10, subfamily R, member 2
chr9_-_8723893 0.401 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chrX_-_138552517 0.400 NM_001171877
NM_001171878
NM_001171879
NM_005369
MCF2



MCF.2 cell line derived transforming sequence



chr12_+_119039075 0.393


chr9_+_2707525 0.393 NM_133497
KCNV2
potassium channel, subfamily V, member 2
chr5_-_94442941 0.391 MCTP1
multiple C2 domains, transmembrane 1
chr12_+_119562737 0.389 NM_001033677
CABP1
calcium binding protein 1
chr1_-_9052207 0.389 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr14_+_75907442 0.383 NM_004452
ESRRB
estrogen-related receptor beta
chr10_-_76488277 0.381 NM_001003892
DUPD1
dual specificity phosphatase and pro isomerase domain containing 1
chr5_+_59819761 0.380 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr17_+_44642587 0.379 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr19_-_55124484 0.379 IL4I1
interleukin 4 induced 1
chr12_-_9777126 0.372 NM_172004
CLECL1
C-type lectin-like 1
chr7_-_56128098 0.368 NM_006213
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr12_+_11693993 0.367 NM_001987
ETV6
ets variant 6
chr1_-_159099090 0.365 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr4_+_147316284 0.364 NM_007080
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_-_122304925 0.364 NM_024873
TNIP3
TNFAIP3 interacting protein 3
chr5_-_138803112 0.360 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr5_+_156540425 0.359 NM_005546
ITK
IL2-inducible T-cell kinase
chr2_+_102294393 0.352 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr1_+_8928508 0.351 NM_001215
CA6
carbonic anhydrase VI
chr9_-_125070675 0.349 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr5_+_140286485 0.346 NM_018898
NM_031882
PCDHAC1

protocadherin alpha subfamily C, 1

chr3_-_114176401 0.346 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr5_-_88155360 0.345 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr9_+_83793506 0.345 NM_001001670
FAM75D1
family with sequence similarity 75, member D1
chrX_+_135079461 0.344 NM_001167819
FHL1
four and a half LIM domains 1
chr6_+_29799182 0.342 HLA-F
major histocompatibility complex, class I, F
chr22_+_38627129 0.342 GRAP2
GRB2-related adaptor protein 2
chr5_-_138803088 0.341 DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr1_-_246869181 0.341 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr3_+_35696119 0.340 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.02 4.53e-08 GO:0006955 immune response
3.12 1.95e-07 GO:0019221 cytokine-mediated signaling pathway
4.86 1.22e-06 GO:0060337 type I interferon-mediated signaling pathway
4.86 1.22e-06 GO:0071357 cellular response to type I interferon
4.78 1.70e-06 GO:0034340 response to type I interferon
2.36 2.44e-06 GO:0045087 innate immune response
1.68 3.79e-06 GO:0002376 immune system process
2.81 5.00e-06 GO:0071345 cellular response to cytokine stimulus
1.80 5.42e-05 GO:0006952 defense response
2.28 4.04e-04 GO:0034097 response to cytokine stimulus
1.58 2.87e-02 GO:0051704 multi-organism process
1.84 2.94e-02 GO:0050776 regulation of immune response

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.66 2.99e-02 GO:0019955 cytokine binding